It seems that you're in Germany. We have a dedicated site for Germany. My aim in writing Gene Function has been to present an up-to-date picture ofthe molecular biology of Escherichia coli. I have not attempted a chronological description, believing that a mechanistic account is more useful for such a highly developed field.
I have divided the book into four parts. Part I is a general introduction to bacterial systems, their genetic material, structure, composition and growth. It has seemed desirable to include herein a brief preview of the remaining text, to introduce the nomenclature and to help place subsequent chapters in perspective. The expression of genetic material and its perturbation through mutation is considered in Part II.
Part III discusses how the transfer of prokaryotic genetic material can be mediated by plasmids and bacteriophages. Escherichia coli in Domestic animals and Humans. Beutin L: Escherichia coli as a pathogen in dogs and cats. Vet Res.
Guyer DM, Kao JS, Mobley HL: Genomic analysis of a pathogenicity island in uropathogenic Escherichia coli CFT distribution of homologous sequences among isolates from patients with pyelonephritis, cystitis, and Catheter-associated bacteriuria and from fecal samples. Infect Immun. Int J Med Microbiol. Microbes Infect.
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Prada J, Zimmermann S, Stephan R, Beutin L: Restriction fragment length polymorphisms associated with alpha-hemolysin determinants are correlating with the expression of alpha-hemolysin in strains of Escherichia coli. Zentralbl Bakteriol. Mol Gen Genet.
Appl Environ Microbiol. Grunig HM, Lebek G: Haemolytic activity and characteristics of plasmid and chromosomally borne hly genes isolated from E.here
gene | Definition, Structure, Expression, & Facts | rowsmillfuncdeword.tk
Zentralbl Bakteriol Mikrobiol Hyg [A]. Hess J, Wels M, Vogel M, Goebel W: Nucleotide sequence of a plasmid-encoded hemolysin determinant and its caomparison with a corresponding chromosomal hemolysin sequence. Prada J, Beutin L: Detection of Escherichia coli alpha-haemolysin genes and their expression in a human faecal strain of Enterobacter cloacae.
J Bacteriol. Strathdee CA, Lo RY: Cloning, nucleotide sequence, and characterization of genes encoding the secretion function of the Pasteurella haemolytica leukotoxin determinant. Frechon D, Le Cam E: Fur ferric uptake regulation protein interaction with target DNA: comparison of gel retardation, footprinting and electron microscopy analyses. Biochem Biophys Res Commun.
BMC Infect Dis. J Antimicrob Chemother.
- Gene Function: E. coli and its Heritable Elements. Robert E. Glass.
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Mol Biol Evol. Res Microbiol. Escherichia coli and Salmonella.
Looking Closer: Recombinant DNA Technology
Mobile DNA. Antimicrob Agents Chemother. J Clin Microbiol. Tajima F, Nei M: Estimation of evolutionary distance between nucleotide sequences. Download references. The authors are grateful to Eckhard Strauch BfR, Berlin for valuable discussions and suggestions and to Karin Pries for technical assistance. Correspondence to Lothar Beutin.
YB took most part in the design and performance of the experimental procedures. Data analysis was performed by both researchers LB and YB as well as interpretation of results and preparation of the manuscript. All authors have read and approved the final manuscript. This article is published under license to BioMed Central Ltd. Reprints and Permissions. Search all BMC articles Search.
Figure 1. Full size image. Figure 2. Figure 3. This gene was present in the common ancestor of eukaryotes. Orthologs for MSH2 Gene. Actinobacteria Mycobacterium tuberculosis African clawed frog Xenopus laevis Alicante grape Vitis vinifera alpha proteobacteria Wolbachia pipientis amoeba Dictyostelium discoideum Archea Pyrococcus horikoshii beta proteobacteria Neisseria meningitidis chimpanzee Pan troglodytes Chromalveolata Phytophthora infestans common water flea Daphnia pulex E. Genes that share paralogs with MSH2: view.
Variation tolerance for MSH2 Gene. Residual Variation Intolerance Score : 8. Gene Damage Index Score : 4. It is characterized by a familial predisposition to early-onset colorectal carcinoma CRC and extra-colonic tumors of the gastrointestinal, urological and female reproductive tracts. Type I is characterized by hereditary predisposition to colorectal cancer, a young age of onset, and carcinoma observed in the proximal colon.
Type II is characterized by increased risk for cancers in certain tissues such as the uterus, ovary, breast, stomach, small intestine, skin, and larynx in addition to the colon. Diagnosis of classical HNPCC is based on the Amsterdam criteria: 3 or more relatives affected by colorectal cancer, one a first degree relative of the other two; 2 or more generation affected; 1 or more colorectal cancers presenting before 50 years of age; exclusion of hereditary polyposis syndromes.
The term 'suspected HNPCC' or 'incomplete HNPCC' can be used to describe families who do not or only partially fulfill the Amsterdam criteria, but in whom a genetic basis for colon cancer is strongly suspected. Most endometrial cancers are adenocarcinomas, cancers that begin in cells that make and release mucus and other fluids. This includes hematological malignancies, central nervous system tumors, Lynch syndrome-associated malignancies such as colorectal tumors as well as multiple intestinal polyps, embryonic tumors and rhabdomyosarcoma.
Multiple cafe-au-lait macules, a feature reminiscent of neurofibromatosis type 1, are often found as first manifestation of the underlying cancer. Colorectal cancer CRC [MIM]: A complex disease characterized by malignant lesions arising from the inner wall of the large intestine the colon and the rectum. Genetic alterations are often associated with progression from premalignant lesion adenoma to invasive adenocarcinoma.
Risk factors for cancer of the colon and rectum include colon polyps, long-standing ulcerative colitis, and genetic family history. Genes that share disorders with MSH2: view. DNA Damage -. Endometrial cancer. Pathways in cancer -. O 20 4 ENSP Q 20 ENSP P 4 ENSP MalaCards Medline Plus.
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